Decidual Cast Shedding & COVID-19

Women around the world are reporting irregular bleeding, alterations to menstrual cycles, pregnancy loss, and more. There are reports of infant girls and elderly women having vaginal bleeding. These events are occurring after exposure to a COVID-19 shot or exposure to someone who recently received a shot. The biological mechanisms of these events have yet to be researched.

A survey studied has been published on one particular symptom reported: decidual cast shedding. This is when a piece of the uterine lining sheds and passes out of the body. Prior to COVID-19 shots, this was extremely rare.

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Abstract

Background: The purpose of this study is to report on the unprecedented rise in decidual cast shedding (DCS) that occurred in 2021. DCS is historically a rare gynecological event, with less than 40 cases reported in the medical literature over the last 109 years. Previous journal articles on DCS were usually case studies; population prevalence data is non-existent.

Methods: The MyCycleStorySM survey was distributed via social media from May 16th, 2021, through December 31, 2021. The total sample size for analysis was 6049 with 89.1% of the participants responding within the first 3.5 months of the 7.5 months duration of the study. In parallel to the survey study, a Google Trends search was completed for search frequencies of relevant keyword terms including “decidual cast” and “decidual cast covid vaccine.”

Results: In the survey, 292 women (4.83 % of the sample) reported having experienced DCS. The mean age of these predominantly non-Hispanic white women was 36.1 ± 0.5 (SEM) years. Eleven percent were taking hormonal contraceptives, 94.3% considered themselves healthy and 96.2% reported that menstrual irregularities started in 2021. According to Google metadata, search terms for “decidual cast shedding” substantially increased during the months of April, May, and June 2021. These peaks in searches represented a 2000% increase over the first quarter of 2021.

Conclusions: There was a significant increase in self-reported DCS in the latter part of 2021 compared to all pre-pandemic cases. More research is urgently needed to investigate the factors contributing to DCS in 2021 and whether this trend is continuing.

Keywords: Decidual Cast Shedding, COVID-19 pandemic, COVID vaccine adverse reactions, spike protein shedding, menstrual abnormality

FULL STUDY

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